Association between Whole Blood Viscosity and Arterial Stiffness in Overweight and Obese Adults

Authors

  • Guo-wei Zhang Department of Cardio-Vascular Surgery, the First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China
  • Ying Li Department of Geriatrics, the Second Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China; International Physical Examination and Healthy Center, the Second Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China
  • Xiu-xia Tian Department of Geriatrics, the Second Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China
  • Rui-tao Wang Department of Geriatrics, the Second Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China

Keywords:

Whole Blood Viscosity, Obese, Brachial-ankle Pulse Wave, Arterial Stiffness

Abstract

Introduction: Obesity plays a key role in the development of cardiovascular diseases. The brachial-ankle pulse wave velocity (baPWV) is an indicator for early atherosclerotic changes. Recently, the effect of changed blood rheology on atherosclerosis has received attention. Our objective in this report is to examine the association of rheological parameters with baPWV in overweight and obese adults.

Methods: In this cross-sectional study, we determined the relationship between rheological parameters and baPWV in 964 subjects (560 men and 404 women) in a general health examination.

Results: Compared with control subjects, baPWV levels were increased in overweight and obese adults. Moreover, there was a positive correlation between baPWV and whole blood viscosity (WBV 3 s-1) in overweight and obese subjects after adjusting confounding factors. Stepwise multiple linear regression analysis revealed that WBV (3 s-1) was a significant determinant for increased baPWV (β = 0.161; P = 0.003).

Conclusion: The findings showed that baPWV and WBV (3 s-1) elevated in overweight and obese adults compared with control subjects. In addition, WBV (3 s-1) was independently associated with baPWV after adjusting other cardiovascular risk factors.

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Published

2014-01-01

How to Cite

Guo-wei Zhang, Ying Li, Xiu-xia Tian, & Rui-tao Wang. (2014). Association between Whole Blood Viscosity and Arterial Stiffness in Overweight and Obese Adults. International Journal of Medical Research, 2(01), 9–13. Retrieved from https://ijmrinternational.in/index.php/ijmr/article/view/35

Issue

Vol. 2 No. 01 (2014)

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Original Research Articles

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