Guillain-Barre Syndrome Following Falciparum Malaria: A Rare Association

Authors

  • Koushik Pan Department of General Medicine, SSKM, IPGME & R, Kolkata, India
  • S Chakrabarti Department of General Medicine, SSKM, IPGME & R, Kolkata, India
  • Anupsarkar Department of General Medicine, SSKM, IPGME & R, Kolkata, India
  • Rajdip Choudhury Department of General Medicine, SSKM, IPGME & R, Kolkata, India
  • Tanmay Samanta Department of General Medicine, SSKM, IPGME & R, Kolkata, India
  • Ritabrata Mitra Department of Chest Medicine, SSKM, IPGME & R, Kolkata, India

Keywords:

Malaria, Guillain-Barré syndrome, Quadriparesis

Abstract

Malarial parasite as a cause of Guillain-Barré syndrome (GBS) is very rare and there are only a very few case reports in literature. Here we report a case of acute flaccid quadriparesis with generalised areflexia following malaria caused by P. falciparum. An adult male developed acute lower motor neuron type of quadriparesis following an episode of microscopically proven Plasmodium falciparum malaria. Clinical examination, cerebrospinal fluid analysis, and nerve conduction studies confirmed the diagnosis of GBS, depicting the rare association of GBS following falciparum malaria.

References

1. Schonberger LB, Hurwitz ES, Katona P et al(1981);Guillain-Barrésyndrome: its epidemiology and association with influenza vaccination. Ann Neurol ; 9 (suppl): 31-8

2. Severe and complicated malaria. World Health Organisa-tion– malaria action programme. Trans R Soc Trop Med Hyg 1986;80: 3-12.

3. Bradley DJ, Newbold CIE, Warrell DA(1987). Malaria. In:Weatherall DJ, Ledingham JGG, Warrell DA (eds). Ox-ford Textbook of Medicine, Oxford University Press, Ox-ford,; pp. 5.474-5.501.

4. Wijesundere A(1992). Guillain-Barré syndrome in Plas-modium falciparum malaria. Postgrad Med J ; 68: 367-77

5. Kanjalkar M, Karnad DR, Narayana RV, Shah PU(1980). Guillain-Barré syndrome following malaria. J Infect ; 38: 48-50.

6. Sokrab TO, Eltahir A et al (2002) . Guillain-Barré syn-drome following acute falciparum malaria. Neurology ; 59: 1281-3.

7. Schonberger, LB, Bregman, DJ, Sullivan-Bolyai, J.S. et a(1979)l. Guillain Barre syndrome following vaccination in the national influenza immunization programme in the United States 1976-1977. Am JEpidemiol , 110: 105-123.

8. Arnason, BGW. Demyelinating polyneuritides(1992). In: Swash, M. & Kennard, C. (eds) Scientific Basis of Clinical Neurology. Churchill Livingstone, London, pp. 105-123.

9. Thomas, PK (1982). Acute idiopathic inflammatory poly-neuropathies (Guillain-Barre syndrome). In: Weatherall, D.J., Ledingham, J.G.G. & Warrell, D.A. (eds) Oxford Text-book of Medicine, Oxford Medical Publications, Oxford, , pp. 21.126-21.127

10. Conner DH, Herber JM(1993). Parasitic infections of theperipheral nervous system. In: Dyck PJ, Thomas PK (eds).Peripheral Neuropathy. Philadelphia: WB Saunders Co.; 2: 1338-90.

11. Shubhakaran, Sharma CM (2003). Acute inflammato-rydemyelinating polyneuropathy with P.falciparum ma-laria JAPI; 51: 223-4.

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Published

2013-07-01

How to Cite

Pan, K., S Chakrabarti, Anupsarkar, Choudhury, R., Samanta, T., & Mitra, R. (2013). Guillain-Barre Syndrome Following Falciparum Malaria: A Rare Association. International Journal of Medical Research, 1(03), 14–16. Retrieved from https://ijmrinternational.in/index.php/ijmr/article/view/25

Issue

Section

Case Report